I've used the Williams sights since the early 1960s, with a blade type front sight. This combination has worked great and simulates the military sight picture (I learned to shoot with the M1). The original "ghost ring" was removing the screw-in aperture and many people use that for hunting applications. I keep the aperture in place. For sighting in I use the smallest one to get a fine sight picture, then swap it out to the medium aperture for hunting.
Several thoughts: The Foolproof with target knobs is spendy, but it is real nice if you are using different loads. If you keep track of the click adjustments when you sight in for the different points of impact, you can just dial in the correct sight setting for the load you are using. The regular Foolproof also has click adjustments which is very nice. The 5D (which cost 5 dollars when it came out, hence the name) and the WGRS have slide adjustments which aren't as precise as the screw adjustments of the Foolproof. If you are sticking to one load they are okay, and of course the WGRS is less obtrusive than the others.
As far as the blade front sight goes, I have mostly used the "Sourdough Patridge" type. They used to be made by Redfield, then by Burris, and the last I bought were made by Marble's. They are a flat blade with the back portion cut at an angle and gold filled. However, my eyes have gotten to the point that the gold becomes a glaring blob in the sun so now I buy plain blade sights for muzzleloaders from Track of the Wolf. That is easier also that I don't have to calculate height. I just buy the tallest one and file it down so my POI is where I want it at 100 yards, with the rear sight in the middle of its adjusting range.
Hope this helps!
-WH-