I agree with staying in the 240 gr range. Garrett and Buffalo Bore make some awesome ammo for the .44 Mag and other calibers, but they are only to be used in T/C, Ruger other heavy built guns.(i.e Contenders, Super Blackhawks, No. 3s, etc) I know that Ruger makes a very solid auto, but in addition to possible feeding and accuracy problems, you may batter the reciever and cause undue wear. I could be wrong, but I have killed some pretty big deer with the Remington 240 gr flatnose and they not only shot well, but handidly dropped deer.