The recoil is harder with the heavier bullets, the 500 grainer being more like a .58 Minnie ball or a 12 gage slug. The 400 grainers are tolerable, and seem to be more appropriate for the rifling twist than the 300 gr weights. The recoil from a Marlin lever gun is harder than the Winchester, which is a heavier rifle, the Marlin would benefit from an octagonal barrel to add weight. The single shot rifles (Hi-wall, Sharps,Rollingblock, etc) are usually fitted with fairly heavy barrels and are not bad recoil-wise, with the exception of the Trapdoor Springfield, which Carbine with a full load is brutal. The Military loaded the Carbine cartridges lighter than the Rifle.
If you get a lever rifle, and use heavy bullets, you need to get bullets with the crimping groove far enough forward to keep the overall length such that the lifter can carry the round up from the magazine. Many 400 gr bullets have a crimp groove further back and the round is too long for the lever action.