I know my dad shot 63g sierras, don't know the exact load he cooked up, but they were wicked deadly on South Texas deer, hogs, whatever else was unlucky enough to get in his crosshairs
seen him take deer out at 400 yards with a 2-7 scope and the heads off of turkeys at 250 yards with that old Sako
he would go to the range and spend the entire day there with several guns and work up different loads there at the range!