Over a decade ago, several members of the Cast Bullet Association made low-volume cases for either .444 or .45-70 loads. As I recall, they achieved great accuracy - but no better than what they could have achieved with normal cases and carefully developed loads.
There are several methods to achieve low ES with the .45-70. One is to use a powder that fills the case to compression, like H4831. Another is to use faster-burning powders (for low velocity loads only!) that bulk up well but ignite easily like Unique, BlueDot or 800-X. Fillers used to be recommended but that practice is generally discouraged today - the risk of chamber damage is real if rare. Lyman used to list numerous loads using case fillers like Dacron; their current manual lists zero loads with case fillers. There is probably a good reason for that....
However, most of us find good accuracy using the loads listed in various published data. I've loaded the .45-70 for over 30 years and have not seen the case capacity to be a detriment to accuracy. OTOH, finding highly accurate .45-70 firearms is a different story.
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