Mine seemed to like the 46 winchester pretty well, the hornady stuff was OK.
Have not reloaded for it yet and I have since converted it to k-hornet, I had to special order dies so I am a few weeks out from load testing.
But really the loading procedure I have been reading should be comparable, this is what I have picked up along the way.
1. Watch the presures
2. Resize as little as possible, neck sizing would be best but not always possible with a handi.
3. Load increments will small during testing +- 0.1 of a grain can make a huge difference
4. Case prep, flashhole deburing and consitant trimmng.
5. Loads could be primer sensitive and some powders do better with pistol primers , there is no actual data but nosler mentions it as one of the options of getting accuracy.
Powder wise I am betting the farm on Lil'Gun, it's not always the top velocity wise (though generally close though) it gives signficantly lower pressures which is desirable with the wimpy hornet case. A good performer if you want to use heavier bullets, in the k-hornet with a 50 gr head it is 200 fps faster than the other powders and again with lower pressures. Supposidly it is one of those powders that do better with pistol primers.
More than once I have read remington brass holds .5 of a grain more powder compared to the others.