Since you're carrying this in a car, why not get a longer barrel than 2" so there's less blast and more velocity? Also, the longer barrel is easier to align thus easier and faster to hit with.
If you were in a defensive situation and you could choose any gun while you are standing there, who would choose any gun with a 2" barrel if a 4" option was available?
Similarly, while the .357 is a good cartridge, velocity is used to compensate for lack of mass. As the saying goes, "Mass has a quality all it's own." The 200gr Silvertip load for the .44 Special runs at about 1,000 ft/sec out of a 4" barrel... just a little hotter than a 185gr HP from a .45 ACP and packs a little more punch (with a lot better bullet) than the famed .45 LC. It WILL hurt, and the lack of blast will make the gun easier to shoot in a defensive situation. Plus, those big holes in the cylinder make speed reloading a little easier. But we're really nitpicking here... any bad guy that you shoot with either the .357 or the .44 will say OUCH! It will just be a little easier on you to shoot the .44.
I have a S&W 696 3" .44 Special, and think this model would be ideal for your situation. Heck, a 5.5" 629 would certainly scare the bejeezus out of any bad guy and with .44 Specials would be one light-recoiling, sweet-shooting, hard-hitting gun. I'm sure that it would conceal well in your car, too.
I'm not prejudiced against similar models from Taurus, although I do think that today's S&W makes the finest revolver in the world PERIOD. The Taurus might be a little rougher but it will still work. BTW, I have found that Taurus revolvers work very well... while I'm not very fond of most Taurus pistols.