Lloyd's reccomendation of a 250 gr LFN for accuracy is correct, but for quick kills I recommend a 220 gr WFN, driven at a comfortable 1400 fps or so. This will work great on game up to elk at least, but don't let a huge grizzly bite you without shooting him first. It is heavy enough for them too, as a defense bullet. I'm presuming that you like the 41 moderate recoil, and this bullet delivers what you are hoping for, with super killing punch. Close as you can get to eating and still having your cake.
Sure, you didn't ask, but for larger game than you are after, get a 44 or 45.