Very simple: Make sure that the crimp is good enough that the bullet doesn't move, while making sure that you've got the best possible contact between neck and bullet bearing surface. In light of this, buckled necks or "cheeto" cases are unacceptable.
It has been shown that crimp level may effect pressure, so it's much easier to do right if you aren't using mixed brass where the case length may vary. I just heavy roll crimp any rimmed pistol case.
Personally, I would much rather deal with a rimmed pistol case than any rifle case.
I used to do seat and crimp as two steps, but now I do both. As you become familiar with this caliber, you will find that you develop a "feeling" for where the die should be set, and you will know when to stop and make small adjustments. If you have a highly uniform set of brass and are making lots of the same load, make use of some good lock rings. I also make "pilot" rounds for faster set up.
EDIT:
As far as setting up for seat and crimp, can I assume you have a single stage press? I back out the die and set the seater plug low to initially seat the bullet. Then I back out the seater plug and adjust for best crimp. Lock ring on die body. Then I twist down the seater plug so that it barely makes contact with the bullet's nose. Lock nut on plug. Viola, seat and crimp in one motion.