I agree with Ireload2 basically. Excessive head space can certainly make the primer back out of the pocket, in fact it is almost a certainly, I would think. The firing pin pushes the case all the way into the chamber. At firing the case grabs the chamber walls locking the case in. The pressure of the shot then backs the primer out. Really look at the primer, is it getting "smeared" where the firing pin makes it's crater after it is opened? Is there a crater or is it blown out too? If it is getting blown back into the firing pin hole, that will lock it up. I guess that if the primer came back hard enough to the beach face it could lock it up too, but that by itself would be a lot of force. As the barrel is opened it would start to pull away from the breach face. Chances are the primer is extruding into the firing pin hole. Some thing else to consider is the primer maybe extruding around the firing pin. This can happen if the firing pin hole is large in comparison to the firing pin itself. I am theorizing here, but it sounds like you have two problems. 1. Too much head space. 2. The primer is extruding into the firing pin hole. Really look at the primer and see if the crater (caused by the firing pin which is normal) is there and if the primer is smeared (obliterated). Excessive pressure can cause primers to back out too. Just because the load shoots fine in one gun, does not make it good for another. I had a 221 FB round that was not hot, but the neck was a little too thick to release the bullet like it should. I had a very high pressure problem on this one. The primer fell out of the pocket. Had to throw that case away. The rest of the cases were OK. That one just did not have the neck turned far enough for some reason. I had turned them twice because the first time was not enough. I must have missed that one on the second time around. You said that the barrel is loose when broken down, does it lock up tight, will it lock up on a .002 thick shim? If your answer to either one of these is no, chances are there is too much head space. You can find answers to this problem in the FAQ sticky. If there is a head space problem, get it fixed and then see if the primers are still backing out. I hope I did not confuse you here. I will try to make it a little more simple. I think you have a head space problem. This may be causing the primers to extrude into the firing pin hole making it difficult to open.

It could be caused by other problems, but I would have to see the primers still in the case after being opened to make a better assessment. it is my 2 cents worth.