I'm about out of IMR 4227, a powder I've used for about 8 years and really like in my .44 Mag. I found a load that works and shoots great in my Ruger Vaquero. I'm switching over to some cast bullets 300 grain, WFN and figure I might go to 2400 to see how well I like it. I'll also load my .357 Mag and possibly some heavy .44 Special loads. IMR 4227 has been a little dirty for me in the past, but shot well. Is 2400 any cleaner? If so, how is accuracy. Essentially, which do folks prefer and why?