The Bond is kinda like a Ruger Vaquero; not a copy of anything historical, but built like a brick (and almost as heavy). The American is very close to an old Remington Derringer in appearance and size. They both have a hammer-block safety, but the Bond does have a rebounding hammer and retracting firing pins, so it's probably a safer carry gun (if that's what you're looking for). I just don't like the looks or weight of the Bond.
I have an American Derringer in .357, and I've been very happy with it.