lymans 48 th edition doesn't show anything in the pistol section for a 250 or 250ai, i'm thinking that even if the twist is faster then 1-14 in your pistol barrel the bullet wouldn't gain enough rpms to stablize a 117 bullet ?... imr 4895 mite be middle ground to try..
?? just a guess on my part
edit ... n't in wouldn't,,,... sorry