I guess I am stepping away from the big boomers. I just traded my M77 .300 Win Mag for a new M70 Featherweight 6.5X55. Now the most powerful bolt gun in my stable is a 7mm Rem Mag. I havent' hunted with the .300 for 10 years, lately preferring to carry the 7mm or my '06. I do still have a Win 1886 45-70, which has some muzzle thump. I guess the point is, for what I hunt (mule deer, elk, antelope) the moderate cartridges are fine, and easier to shoot, to boot.
Tom