I haven't shot any deer and only one small caribou with Corbon 265 gr hard cast. That may have been too much of a good thing for the small animal - about 100 lbs and I got full penetration. I'd use a top load of H110 and the 210 Hornady XTP - seems like it gets a lot of good press on here. Or H110 with the Speer 220. I've been loading some 250 jackted bullets I get from a guy in Oregon (see Gray Beards' New Produts forum). But I haven't shot enough of them to have a good load. Just loaded some round 2 nights ago. Good bullets but again mighty heavy for smaller animals. I'm loading them for my Marlin Rifle and Redhawk. Good luck and I hope you post a picture of success.