That is a personal choice. Personally, when I get a round developed that shoots sub .5 MOA consistently for my varmint rigs, I have found my load. I look at sub 1 MOA consistently for my hunting loads. I might be able to work at getting them better, but I have several guns, and at least one of them is under load development one time or another because, it is new or I changed stocks, some thing. In my original load development, I use bullets that I want to use in the field. I do not use full metal jackets, develop a load for it and then switch to a V-MAX. I only develop loads that I will be using.