It is amazing how the original post on this question is so parallel to what bullets and rounds were effective on African game, both DG and plains. Kevin Robertson, a vet and pro African hunter, in his book "The Perfect Shot" iterates these same posts. With all the new ultra high velocity rounds, the bullets manufactured are for a range of velocities and what works at 300 yards with high velocity may not work at 50 due the bullet breaking up from too high a velocity impact. Corelokt bullets are effective for the velocity range intended. Not for 25 yards shots at above 3000 fps. This requires a premium bullet for the velocity. It has always amazed me that very good and knowledgeable hunters ignore the simple facts of physics when it comes to cartridge comparisons. When a cartridge is effective at all normal hunting ranges with a particular weight bullet, some screwball decides a lighter bullet with a flatter trajectory is better just because energy values are higher. And if it is better, then a round that shoots one 200 fps is much better, when in fact this is just not true. An example. A 300 Win Mag shoots a 200 gr bullet at around 2800 fps in traditional length hunting barrels. A .338-06 shoots a 200 gr at 2750 fps. The .300 has more energy, flatter trajectory, and more sectional density but doesn't hit any harder on game. Using a KO formula for game, one must take into account bullet diameter and cross sectional area. The .338-06 has a KO value of 26.5, while the .300 has a KO of 24.6. Now I agree that this is not enough difference with the same weight bullet. But go to a heavier bullet in the .338 having the same sectional density as the 200 gr .308 and the difference now is substantially in favor of the .338 and with a bullet designed for the range and velocity for proper expansion and penetration. The 300 Win Mag using 200 gr at the KO value of 24.6 is way out of its league when the 250 gr .338-06 has a KO value of 30.2, with a higher sectional density bullet and much less energy. No wonder moderate velocity rounds at normal hunting distances have worked so well over the years due bullets designed for the velocity intended, and impact velocities for proper expansion. These are the mathematical and physical facts as realized by anyone with a calculator. Argue all anyone wants to, the facts bear this out on game.