I had high hopes that the 410 slug would be a good choice for some kinds of hunting but learned that the slugs only weigh 90 to 100 grains. That cooled my interest in the 410 slug as a hunting cartridge except for perhaps turkey hunting.
So check the full ballistics before deciding on a 410 slugger.
On the accuracy question: I have often read and heard that each barrel is a law unto itself and that the only way to find out about a gun's accuracy is to actually try it out. That's especially true when shooting slugs in smoothbore barrels. For example, my son's old 20 gauge Mossberg 500 Bantam shoots fabulously well with Rottweil 2 3/4" slugs. Groups are about 3" at 50 yards. Wow! But the same gun with Federal slugs doesn't even reliably hit a deer sized target at that range. I had to try several brands of slug before finding a good one for that gun.
I tried the same slugs in my Beretta 20 gauge and found that it shot all of them well. So it wasn't the slug, it was the combination of gun and slug together.