I have zero experience with this round, but I load a .338/.378 Wby. for a friend that primarily whitetail hunts with it, and plans to hunt Alaska with it. He wanted a whitetail load and an Alaska load, I loaded him some 250 gr. Nosler Partitions and said, "here, you can do anything that walks in North America with this load" He said, "I want a super-fast, big varmint load for whitetails so they won't run far" I loaded him some 180 gr. Ballistic tips with great reluctance, and they flatten whitetails, destroy pounds of meat, and don't penetrate as well as I think they should, but he loves them. I made him shoot a deer with the 250 gr. load last year to see how it did, it knocks them off their feet, literally, at 200 yds, and wrecked about 1-2 pounds of meat in the shoulder, but very good penetration (it penetrated through the poplar tree behind the deer) I'd go for a heavy bullet, like a Nosler Partition or a Swift A-Frame, and get an accurate load for it, it will do anything you need it to.
Selmer