I have no skills to calculate the strength of any material. I rely only on what has been done by others and worked. I have a .22 Mag barrel that has a scout mount scope that has only about .040 to the bore from the scope base holes, and it has never blown one of those, my guess is that the .150 is way over what is needed with a #6 sized hole, however I have no data to prove it one way or the other. I also don't know how you assign an amount of strength to the dovetail that you drive into the barrel to lock it, on this project I used a threaded collar at the breach and a driven in pin at the front of the barrel, it didn't blow up so I guess it is more than is needed. Wish I could offer some calculations to you, but I just do not have the skills for it. Larry