I'll get bombarded with "you're a fool" with my response but carrying heavy rifles around has never bothered me. I'm in excellent shape though, lift light weights for 20 minutes a day, 4x a week, the big + for me is that I jog 8 to 12 miles every other day so I could hike forever without feeling winded. I've carried my rifle and a 30lb backpack into some of the rougher PA hills for miles and my mind was wandering, thinking about the hunt so carrying the backpack plus the 13-14lb rifle doesn't phase me a bit.
This probably will change with age but as of right now, a mountain rifle with the mounts and scopes and bipod I like would still weigh in at around 10 lbs. If I can carry 10, I can carry 13 or 14, see where Im going with this? It's not a big enough jump in weight to bother me. A nice comfy sling is the clincher, get one and you won't regret it. If you're in decent shape and shoot confidently with the Sendero, well there's your answer.
The thicker barrel doesn't necessarily mean better accuracy although after several shots, the heat won't affect it as much as it would a sporte, but this is hunting you're talking about so 1 shot, maybe 2 will sound off so barrel thickness shouldn't be a concern here.
The excellent stock that the action/barrel sit in will help overall accuracy in inclement weather, that's more important.
If you shoot the same caliber in a lighter rifle and a sendero, and you're much more confident with one, go with that. I'd rather see someone expend a little more energy by carrying a heavier rifle but shoot with confidence rather than running around some land with their lighter rifle only to end up shooting at something with less confidence. Am I making any sense? 
To end my rant....The Sendero overall is a very highly regarded model and for good reason. Fit and finish is excellent(it should be for the price) and are extremely accurate and handle the larger calibers with ease 
Yep to all of that!!
None of us can answer whether or not you would regret the extra weight. There is
NO ideal weight for all hunters, despite what some gun writers say & one size/weight does not fit all. This varies with fitness level, strength & what we are used to & of course age. Sadly, so many even
young people are couch potatoes that it is pathetic & just hiking in Elk country is too much for them & that would be without carrying a rifle at all.
Among hunters, some can carry a 10# rifle easier than others can carry a 6# rifle. The last Elk hunt that I had I was at 9,500-10,000' & I carried my 300WM Sendero on all day hunts. Frankly, it would have been fine if the rifle was heavier, but I am relately fit @ over 6'1" & 250#, in college days I did a little powerlifting & had an athletic & construction/farm working background, so it is all relative. This sounds funny, but a couple of weeks ago I handed my youngest son my 308VS (bull barrel) with a 6X18 Leu. & he commented, hey it's feels a little light. I thought at that moment how diff.
the reaction would have been if I had handed the same rifle to many members of this forum, but keep in mind this boy lifts weights & has been sparing with my middle son who fights MMA, so he is certainly not the average sendentary citizen. God has blessed me with good health & I know that my feelings toward rifle weight could change overnite, but that's the way I see it now. My point is on the weight side of the question, only you can answer that. You could see if you could borrow someone's Varmit rifle, carry it all day & then you will know.
On the pure accuracy side of the question, when comparing a heavy barreled rifle with the same quality components & workmanship as a light rifle,
the heavy will be more accurate/consistant. And we need to remember the quality of workmanship & materials has more to do with it than sheer
size/weight. This closely compares with scope technology as well, for example a 30MM scope & a 50MM bell with the top quality glass will be brighter
than a 1" 36MM bell scope with the same quality glass with the setting on say 10X in dim lite, the big scope will whip it bad. But if the big scope
has cheap optics & you compare with the small scope with top glass, then the picture changes. So, quality is more important but the bull barrel
properly bedded wins against same quality smaller tube. This is how you can have a fluke situation as Dee did, the BDL was probably put together a little better, it happens with production rifles. I traded for a 270 ADL last summer that is too accurate for the type of rifle it is, but I like it & don't care, I just enjoy it.
But as in scopes, if you compare the heavy & light of the samre quality, the heavy will come out on top.
This is why you don't see small tubed target guns, but in fairness part of this is because of consistancy in shot strings & in a hunting rifle that is not an issue. But it also has to do with vibrations, a stiffer rifle is more forgiveing & capable of smaller groups. Even if a very serious Varmiter is doing low volume shooting such as Western Rock Chucks, he is better served with a heavy, stiff rifle & can achieve
SLIGHTLY tighter groups.
Which is also why the Mil. does not use small tubed rifles as their sniper rifles, despite the fact that those boys have alot to carry. Concerning the Rem. Sendero, I have shot alot of those & they are usually real shooters. I have seen one that did not do as it should & I have seen Rem. sporters like my 270 that are extreme, but overall you can expect better groups than with the std. 700. They have a stiff stock with alum bedding, a better set up than Mattel plastic or wood. They benefit from skim bedding, as the std. will benefit with a quality pillar/glass bed, but the Sendero stock is better off as-is than the reg. 700 as-is, it is a stiffer platform period. Some have told me that the Sendero has an upgraded barrel, not as much as a 40Rangemaster or a 5R, but an upgrade. Well, I cannot prove that one, but it is sure not unusual for the Sendero to look better with a bore scope.
I don't own one of those but a gunsmith friend does & I bug him alot.
Let's just say that if you pull a Sendero out of the box & a reg. 700, I would put my money on the Sendero & over time I would be money ahead.
We talked about the weight & is it heavy for you & the pure accuracy component , now let's look at you shooting it in the field. Graybeard does have some good points concerning this. He says "from field positions most commonly used in hunting no one is MOA that I've ever seen shoot".
I agree in part with that where he says "field positions most commonly used in hunting", too me that means for the ave. Deer hunter, yea pretty much. But I also know that from some of my tree stands while using a good rest I can hold the heavier rifle more steady than a light rifle, which translates to better shooting. Whether for me that means 2.5" with a tree stand rest with the std. as oposed to 1.5" with the heavy or whatever the size group is, it matters when the range gets longer. Also, I will mention a field position that is not "most commonly used in hunting", but one I have used out West & even here in AR at the edge of crop fields. I use a harris bipod in the front & a "poly" bean bag in the rear. This "bean bag"
weighs almost nothing & I can carry it in a BDU size pocket. I have practiced this & I can get into this position in seconds. This 3-point field postion is rock steady & yes with a 1/4" Sendero like my 25-06AI or 300Wm you can shoot MOA in the field, but I know this is not the "field position most
commonly used in hunting" & for those common field positions Mr. Graybeard has a valid point. With this same 3-point system, the light rifle does not do quite as well.
Another factor to is the wind. Try holding a light rifle in a crosswind & then try a heavy & you will find you can steady a heavy much better, it is windy out west.
To me this stuff is not a big deal except for the most disciplined shooter & for those who want to be able to shoot a little further, not talking about shooting a mile here. If this is you & the weight doen't bother you then the Sendero can give you an edge.
