I think the ability to handle pain...of any kind...is personal. Some peole have a higher threshold than others. The ability to handle rifle recoil is also a learned response. I have lots of projects going on all the time and my own range so I'm shooting something on a daily basis. I've learned, tho', that if I want to get the best targets from small calibers when developing the highest accuracy I better shoot them BEFORE I break out the biggies. The human body can absorb just so much energy in the form of recoil before it starts rebelling.
Right now I'm shooting up some 30 year old Hornady 200 gr 338 bullets using the same load I first developed. After 20 rounds my body is vibrating...literaly...the recoil isn't bothersome but the number of rounds adds up...and the rifle needs cleaning by then.
Any caliber can be loaded up or down so use the lighter loads for practice and work out a good heavy load for hunting. I have a couple of 525 gr loads for my 45-70 I only use for hunting you see...I don't like to waste those big plugs on paper and I have several 300 gr loads for "plinking".
I bought several boxes of Rem 405 45-70 when I first acquired my BC and was surprized how little recoil they generated. From hearing all the stories and reading the posts online I figured I was in for some real pain. It just goes to show we men need to be hairy legged whether it's real or not.
On another note...I think I've taken as many deer with a 22 LR than I've taked with the rest of my shooters. I don't recommend it due to the legality aspect, but sticking a round in the eye will give you venison steaks anytime...as long as you're close enough and have the ability.
'Njoy