If you are concerned about the 300 grain Hollow points above about 2200 fps then you might want to go with the Hornady 350 Round Noses, give up a little velocity, gain some ballistics. You can move hornady 350s fast enough to expand, the speer 350s might not, they are really a 458 bullet, they even come with instructions that say so. I like cast bullets, but I like the 350 rns alot too.
regards,
Graycg