Don't worry about it, I have a bunch that are off center, some by a lot, but they shoot just fine, no different than those that are centered or just a little off center. as I posted before when you brought this issue up in another thread, my .444 has off center strikes and is one of the most consistently accurate H&Rs I own. I suppose the anvil configuration on some primers might be a problem for a really off center pin strike, if they are, just don't use those primers!!
I'd say not following thru with trigger pull would be more to blame for inconsistent accuracy. If it's off center bad enough to cause misfires, H&R will replace the barrel.
Tim
Check the firing pin if it is off center very much it will cause erratic groups.Please let us know if it is off center.