I had one of those shoulder cannons
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with the ported 18 1/2barrel from Marlin no less.
I presume you know that this round was created to give a full bore, pedal to the metal 45-70 Govt load for folks that didn't want to handload their 45-70 Govt rifles to full potential.
The factory ammo will fill your hunting requirement . Their flex tip is available now for the reloader as well. That would not be my choice for grizzlies however. If you can work out a load combo that puts a 350 gr Hornady RN or FN for close range and the Flex tip for 100+ yards into a useful zero you have a great setup.
If you want less pain you can use the same bullet loaded down. I tried loading the Speer 350 gr bullet and found the cannelure in the wrong place to work. Loading the round was no problem but getting an unfired load thru the ejection port of the Marlin rifle was not possible without seating the bullet much deeper. That presented another problem because the taper of the bullet started and the case mouth would have to be crimped severely. I don't know if that would be an issue with the Browning.
I believe Barnes still makes several weight Original style as well as TSX bullets in.458