Depends on the stand and my mood.
Generally speaking, short range stands, Marlin GG in 45/70. Longer range, either 30/06 Rem 700 or 25/06 Ruger 77 or 280 Ruger#1.
This year I will add the Handi Slug gun to short range.
Later in the season when I'm getting tired of shooting Deer only, Remington OU in 308-12 ga.