Now those who say the Smith & Wesson "Airweights" are not a good choice because people load them to hot are badmouthing a very good self-defense weapon! If your a man and can take the recoil fine and dandy but if your a women and can not, they simply load the pistol with .38-spl 125 grain bullets and be ready to rock N roll. A plan jane .38spl up close is far better than a hammer or baseball bat!
The big problem for a lot of older women and young too, is pulling back the trigger on the double action pistol and being able to hit the target. Most I have found will shoot a foot low for starters! Some double actions I have tested are in the 7 to 10 pound pull range and women just can NOT handle that while pulling back and yet keep the pistol on the target to hit their mark. Nothing wrong with a Lady Smith in .38-spl. as it was made for ladies in the first place.
The Glock slide is one of the friendliest to operate and yet the trigger pull if very manageable for just about anyone regardless of age or strength. This is why my wife carry's a Glock, she can everytime on the firing line, draw and fire her Glock .40 cal and hit the mark with the first shot. I feel this is very important, as you can not afford to give the Bad Guy a Free missed shot! The Glock also generates less felt recoil to the hand because of the way it is made. A big plus for women in that respect!!!