They all look good. The choices for personnel defense are great these days. I looked at a chart of one stop shots. The barrel length made a difference as did the load, (357 mag 125 grain high velocity vs the med velocity had a big difference in one stop shots.) The new stuff made to expand at lower velocities should be a huge help. I wouldn't be too concernced with accuracy with each load, unless your going target shooting. I'm a big advocate of point shooting. If you have time, cover or distance you will probably use your sights. Most violent acts are sudden and under ten yards, (how many rooms in your house are longer than thirty feet, or how many people rob you at more than an arms length away.) 80 + police shootings caught on video and most if not all show the officer not using his/her sights, even though they are trained to use sights. Also you are likely to be using one handed shooting, (turning on a light with the other hand, holding a phone or flashlight or car keys...) Anyone thinking about home defense should look at the tragedy in my State this week, Mont Vernon NH four scumbags broke into a home at 4am and butchered the mother and eleven year old daughter, all for a B&E! Thank god the daughter pulled through.