Without question, it is always better to keep rifle brass separated as to number of times fired, make AND LOT NUMBER!!!!!!!!
Some years back, I was working with young son's 30/06, trying to develop some good hunting loads.
It was about an hours drive to the range we were using, so wanted to make the trip worth the expense/time.
Loading the series of test loads, I ran out of brass from the son's supply so went to my "brass stash" and picked out some 06 brass.
I seperated the brass as per brand/maker, AND by style/type of head stamp, then trimmed to length and loaded the test rounds using the same brand (Remington) and head stamp style.
This brass happened to be used for the higher pressure test groups, the last two as I recall, and there were two or three pieces of this "stash" brass in each of those 5 shoot groups.
Well, when those rounds got fired, the "stash" cases not only shot out of the groups, but showed excessive presures.
One case went from "trim to length" to inexcess of the "needs to be trimmed length" in that one shot.
I now make it a practice to use mixed and "range" brass for what I call "banger" brass, meaning brass used for practice and reduced pressure loads.
As stated by GB and others above, weighing the brass would be a smart move even with mixed lots of same brand brass.
Keep em coming!
CDOC