The 454 Casull is just an extended 45 Colt round. Extended so it will not chamber, in a firearm properly chambered for the .45 Colt cartridge.
I would shoot a .45 Colt round, in a firearm, chambered for the .454 Casull caliber cartridge.
However, I absolutely would not shoot a .454 Casull round, in any firearm, chambered for .45 Colt cartridge, regardless whether the firearm would chamber the round, or not...
Bill