I would say yes with some reservations. I have a Sportview 4-12X40 on my Hornet barrel that I use for Hunter Pistol. It does not have a target turret but since the Hornet shoots so flat that I only change 4 clicks from chickens to rams. It has been a very good scope and the repeatability from rams to chickens has been good. My reservation is that I cannot comment on repeatability when you are turning the turret up and down as much as you would need to with a 22LR. I suspect it will work just fine.
Sixgun