Irold-
Each gun is different as far as bore finish, as well as dimentions. I have a few that will only shoot well with a gas check, but most do well as long as the bullet is cast on the hard side, sized to the bore, maybe .001 or so over. I size to .431 usually. If you have a gun with chamber mouths that are way out of spec, that can be a real problem. Older colts were well known for that. Undersized mouths can be opened up to match the bore without to much trouble, oversized mouths are a bigger problem. With oversized mouths, you are better off sizing between the chamber mouth and bore diamiter, using a softer bullet at moderate velocity, so the bullet will expand or compress as needed for a good fit, at least that was my experience with one 2nd gen. Colt SAA in .45 lc that I had.
Wyo-
Thanks. I hate to say it, because I really like the look of a nice SA, but you are right, a DA Smith, fired SA, with good fitting grips, is hard to beat. I think the larger your hand, the harder it is to shoot a Colt style SA revolver. Guns just as accurate, just harder to shoot, at least for me. Find I have to concentrate a bit more to get the results my smiths just seem to have with ease. You dont hear a lot about Red Dot in handguns, but it works real well in big bore revolvers for light - mid range loads. I usually don't like noting specific loads, but will say thousands of 6.0 to 6.5 grain loads of Red Dot behind a 240 grain bullet in dozens of revolvers has proven to be a safe and accurate plinking/target/small game load. About 8-850 fps, depending on the gun.
Larry