Not sure what the Hornady XLT bullet is, it's not listed on the Hornady site but I use the 250 and 300 grain XTPs for my Ruger Blackhawk (4 5/8") and Winny Trapper. The Trapper likes the 250 gr load over the 300 grain as well and I load it with 20 gr of 2400, shoots good in both the Trapper and the BH. The BH likes my 300 gr XTP load better as well, 20 gr of 296. Note: both loads are low to mid level Ruger/TC loads, don't see any since in pushing the limit when these loads do the job and shoot plenty accurate.
Regards,
Shvlhead.45