My favorite reduced loads for my 30-06 include a gallery or "squib" load of a single"O" buck shot lubed with Lee Alox and 3 grains of Bullseye. 1300fps and very accurate at 50 ft.( Don't reuse these cases for any other loads, only squibs)
110 grain M1 carbine bullet, 19 grains SR 4759-1900fps and hits point of aim at 100 yds when my hunting load is sighted in 3 inches high at that range-great practice load. 4350 is one powder NOT to go below listed charges with. The Speer, Lyman and Lee manuals are the best sources of reduced load information. If you don't have any of those manuals, buy the Lyman and Lee and get a loadbook for 270 as that will have the Speer info in it.