I reload the 125gr sierra spitzer for my 06 most acurate bullet i have shot in the old ruger mark2, 3 shot group at a hundred yards can be covered with a nickle, i shot a doe 2009 season quatering to me at about 60 yards hit hear in front left shoulder and came out behind right front shoulder, did alott of meat damage but the bullet worked dead deer. i think this bullet would work well on futher away shoots and in the lung and heart area,to me its not a should shoot bullet,but the bullet is very acurate in my rifle