Mac makes a good point, getting ready for 2009 deer season I swapped the original laminated stock out on my 25-06 Ultra for the new style synthetic stock to make it lighter to carry, using both loads that shot good in it, groups went from two shots touching to 3" groups at 100yds!! Being short of range time to work up a new load, I chose to swap the stock set back, by that time I'd used up most of the factory ammo that shot good, so I tried a third factory load which still shot under an inch with the factory lams. So as Mac said, be prepared to start all over again dialing them in if you do swap stocks.
Tim