Is a 10mm not a .40 caliber? Why chose that, when so many other calibers are available? IMO, it's a police round. I wouldn't want a .357 Sig as my primary hunting handgun; neither would I chose a 9mm. The reality is, some rounds are developed with specific functions in mind, albeit they are sometimes interchangeable as to purpose, but for hunting only, it's silly to consider multi-purpose rounds. Use what works the best, not what might work.