A couple of friends "twisted my arm" and we all three bought Ruger SS Bisley .45 Colt/.45 ACP revolvers some months ago. They were all finished extremely well, in my opinion. They all needed a trigger job and all six cylinders (throats) were undersized. I borrowed a Manson Reamer Kit made for the job from another good friend and reamed all six of them. After the trigger job (I also had the original pawl modified to a "free spin pawl") and cylinder reaming, all three of these revolvers shoot extremely well.
You might think from the above that I am complaining about he undersize cylinder throats. However, that is not true. I consider that we all have custom throats on our revolvers and the performance is enhanced immeasurably. Before reaming the throats, mine started leading from the first shot and by the twentieth shot was no longer "on call". Now, I can shoot several hundred loads with NO leading and accuracy is maintained from the first shot to the last.
I consider this combination one of the most desirable handguns to be had. It makes a tremendous range gun with the .45 ACP cylinder and with the .45 Colt, you can load and use very powerful loads for hunting big game. I cast my own bullets and reload, so that is a plus for me.
This is my revolver with the .45 ACP cylinder:
FWIW
Dale53