Like the larger Ruger 77s, the action is one of the easiest to fit a new barrel to. Factory barrels on 2 of these rifles were removed and cut to "K" chambers and reinstalled. They were not tight at all and the weight of the action wrench was about all the torque needed to get them started when UNscrewing from the action.
What are you wanting to chamber to? 17 Ackley Hornet is one I've thought about doing but went with another action instead because of the Ruger 2 piece bolt and it's side movement, at least on the one I had.
Might still try it one day if another 77/22H comes around.