I had a .270 handi, I never killed a deer with it but a friend used it to take 2 mulies before he bought it from me. We have a few bolt .270s in the family and they work well on hogs and very good on deer.
I like a 130 gr bullet. Speer or Nosler work well, I have not taken game with the sierra bullets yet but they print well on paper too. Hope you have good luck. You will get many thoughts on bullets, if you find one constructed for hunting big game and it hits where you are aiming, it will work. The .270 is a very impressive caliber. thejanitor