That 48 grains will loosen you dentures.
I use 30.3 grains of IMR 4198 under a 400 grain JSP Speer bullet.
Accurate and easy on the shoulder load.
Personally I don't care for a lot of recoil, and 1500 fps is about my max when it comes to big heavy bullets, but 1200 to 1500 fps. is plenty for deer using a 405 grain bullet.