Weak spots? on a Ruger?
Well, I do know the desire to customize/modify, etc. ...........but other than a lighter trigger return spring, which nobody will see, or a high viz front blade/bead and an express rear configuration (shallow V) that works for some and not others, I would use as is and be satisfied that I had one of the best handguns ever built!
BTW, I have the 50th aniv. 357 and it is 'mag'nificent (with a stabilized spalted maple gripset from privatescustomgrips.com on it), so I know whatof you speak.