I use it only in the 375 Winchester. It gives me the most velocity with the 220 gr bullets. From our typical cool winter days to the heat of South Texas, it can change the velocity by 150'ps from coldest to hottest. Doesn't seem to effect accuracy or POI thought in this particular cartridge. I didn't see what cartridge yer loading for but if the heat is a factor, might to look to TAC, if it'll work for you. My next round of powder buying will include TAC for a lot of my loading. It's cheaper, clean burning, and extremely temperature stable.