All things equal Canada will be more expensive, involve more red tape, and will require a passport.
It costs $30(?) to register your gun, though that requirement may have gone away last month. Gas is roughly a buck a gallon higher. Everything you see or touch is more expensive and not just a bit either. The passport will run about $100. Quads mean proof of insurance, registration tags and helmets.
Customs can be as simple as a toll booth, well maybe not that easy but close. On the other hand, cavity searches are not out of the realm of possibility. Most likely you will unload all your crap to be x-rayed and tossed. Load the truck expecting it and it ain't terrible. We got to using one size of rubbermade tote. Loaded our stuff into about 8 of them plus gun cases and a ruck sack for each person. It was a very simple process loading and unloading. The Gypsy looking rigs were tossed vigorously from my observation.
However, there is something about crossing the border that adds to the adventure. I'm not sure what it is, but there is a certain excitement that comes from being in the north country.
Investigate what happens to a trophy if taken. By that I mean how far are you from a freezer? If one is days away, that hide might go sour if taken opening day and you are waiting till the end of the week and temps start climbing. If it hits the freezer next morning it will be golden when you leave the bush to head for home with a -15 degree cooler of meat and hide.
Staying in a cabin vs staying in a tent. Showers ? Camp cooking vs kitchen cooking? Level of personal service? Shithouse or dig your own? Cut wood or gas stove? North country and mountain wood is like news print if you are unfamiliar.
It might be the smaller things that set one apart. DO check references, demand several unsuccessful hunters in your phone list. A reasonable hunter can be satisfied with a hunt even though no game was taken. You can get a feel for how hard a guide will work when game is scarce, not when plentyful.