Ive been looking at that 22/45 Lite, but then, for me, carry weight is important, I mostly dont want to notice it until I want it. I played with a 22/45 soon after they came out and it was very good, especially for some one with a 1911 (doesnt feel exactly the same, but WAY closer than the original that'll hunt 'coons until you re-adapt). Im not a fan of the take down, but it isnt like you have to do it all the time.
Just food for thought, how about the other 22LR 1911 style guns out there now?