For me, there aren't many 40 cal bullets to choose from. On the other hand, the 375 has plenty. With that said, I haven't heard on any "cats" on the 450 yet. That's not saying the don't exsist. Somebody else may reply that has heard of something.
My first thoughts were to go with a VVC rounds, based on the 45-70 case. But there is .007" difference in the case heads, with the 45-70 being smaller. Then again you could open the 375 VVC up a little and make it work. Also I don't think VVC has a 40 cal. .
Now, food for thought. If I were doing something as such. I would neck up 4 new 350 Rem Mag to .375. Stuff 260 gr NP's in them, (for particular OAL for action used), and send 2 toe Redding for dies, and 2 to your gunsmith for reamers. The 350 is slightly longer than the 450. Which may not be desirable in your action. You can get forming dies and neck down the 450 also. Either way it could be costly,,,,But FUN.