Well, I guess if the 40 and 10mm were rimmed and shot out of a revolver it would work. Being rimless and from a semi-auto, I could see where it could be a problem. Like the 460 Rowand or Roland? in a 45 acp. You have to change the uppersto work, or change the barrels and springs and the barrel has a muzzle break on it. To me, I don't think you need a 10mm unless you want a semiauto in bear country.