I do not know enough about plastics and ploymers to say for sure.
But what I do understand is the barrel can not be rifled that builds pressure and created deadly projectiles.
Like the 3 D model gun in the CSI NY show. It would be interesting to see it shoot more than once and at what point the gun will fail.
I find the choice of a 380 odd when something like 38-40 has less pressure
380 = 21,000 CUP
38-40 = 14,000 CUP
pluse 38-40 has a rim that would make chambering easier. As the 380 would have to chamber on the mouth of the case and the rim is what can be used to chamber the round.
I also find it hard ot believe that a plastic firing pin broke the primer.
Now I will believe that the gun could have a steel barrel liner, a steel firing pin, and a steel or possibly alloy like Brass or bronze block that holds the pressure in. '
Having watched Myth Busters a number of times I will say that the gun is not real, at least not as advertised. That there were probably two models, the enhanced model that can shoot and the one they take apart to show how it is all plastic / polymer.
I also find it hard to believe the 3D printer that uses sheets of plastic as thick as a sheet of note book paper and the pages are glued together or heated will not stand the pressure. The 3D printer model may have been used to make molds that were poured like injection molding. Or a solid block of Plastic was set in a CNC machine and made based on the 3D models.