I'll keep my 1911 and .460 Smith, thank you. I shot a standing Grizzly with the .460 Smith and it literally knocked it over backwards.
I've personally seen people shot with .22LR, 9MM, .44 Mag, and .45 ACP. The people shot with the .22 (me among them) sure did a lot of screaming, but they never went down. The people shot with the 9MM did not always go down. They may die shortly thereafter, but they had plenty of time and capability to shoot back. The .44 mag and the .45 acp, lights out. They went down and did not get back up.
The first man I ever saw shot was shot with a 1911 Colt in .45 ACP. I was 17 at the time. My Boss pushed me against the wall, pulled his 1911 and shot three shots at a wouldbe robber. This man was holding a gun on two cashiers. My Boss was an Ex-Marine, just back from VN. He hit this guy all three times, knocking him back against the windows, then he fell to the floor. The guy kicked a few times then went limp. He never tried to get up.
The day Mike Smith accidentally shot me in the right side with a .22 revolver I screamed. I jumped up and down a few times as I turned around in circles. Then I got mad, I looked at Mike standing there with his mouth open. I grabbed the gun from his hands, and laid it up side his head. Knocked poor Mike to the ground, then I threw the gun out into the lake. The hammer split Mikes ear from about the middle up. Then cut his skin above the ear for about two inches. The guys later said he bled worse than I did. I pulled my Jacket, shirt, and tee shirt up to where I could see the damage done. There was a small hole leaking blood. I put my handkerchief over it and ran to my car. Ed Read forced me into the passengers seat, I was going to drive. Ed drove me to the Hospital, where they removed the bullet. They kept me in the hospital for a week. Today I look at that small scar and laugh about it. I feel guilty about Smitty's ear. He was scared for life, in a place were he can't hide it.