For rifle, I do the following if accuracy is the only objective:
Use 25 or 50 cases for testing, all the same lot, all the same primers, all prepared by FL sizing, if new or fired in another rifle. All neck sized, if fired in the test rifle. (bolt action only)
Use 5 shot groups.
Divide the difference between min and max charges into equal increments.
Load the cases using a seating depth of .020" off the lands or maximum SAAMI OAL for your magazine.
Shoot five or ten groups of five shots each and measure the groups for accuracy.
(Sometimes, I eliminate the worst shot of the five, and measure 4-shot groups for accuracy. That eliminates any pulled shots that are your fault.)
Once you've determined the best accuracy, load up more cartridges between the best group and your test powder charges before and after it. This will further identify your rifle's best powder charge.
If you are not limited to a specific OAL by your magazine, you can now load up more test cartridges using your best powder charge, and varying the seating depth of the bullet. I suggest testing in .005" to .010" increments in each direction from your original seating depth.
Once again, shoot for accuracy to determine your best load.
You've now got your "best" load.
Changing any of the components, (or sometimes, lot numbers), may necessitate your doing everything over again! Since I don't like testing forever, I find the load my rifle likes.......and then I have fun shooting it.
For a few rifles, I have more than one loading. This is usually because I want to change bullets.
It is absolutely necessary to keep good reloading records. Everyone has their own way of doing that, but mine is a 3x5 index card file.
hogship